| Characteristic | Details |
|---|---|
| Name | Misoprostol |
| Formulation | Tablets |
| Strengths | 100 mcg, 200 mcg |
| Route of Administration | Oral |
| Usage | Gastroprotective agent, labor induction |
| Explore Misoprostol Further | |
Pharmacokinetics
Misoprostol, an analog of prostaglandin E1, integrates into pharmaceutical therapy due to its unique metabolic pathway. Oral administration leads to rapid absorption. The compound reaches peak plasma levels within 30 minutes. Misoprostol undergoes de-esterification to its active form, misoprostol acid. The acid exhibits a half-life of approximately 20 to 40 minutes. This pharmacokinetic profile influences dosing schedules.
Misoprostol acid displays extensive binding to plasma proteins. The hepatic system primarily manages its metabolism. Excretion occurs via renal pathways. Pharmacokinetic variability arises from inter-individual differences. Such variability necessitates tailored therapeutic regimens.
Dosage Information
Misoprostol tablets are available in strengths of 100 mcg and 200 mcg. Dosage depends on the intended indication. For gastric protection, the recommended dose is 200 mcg four times daily with food. For labor induction, dosages vary based on clinical protocols.
Healthcare providers should evaluate patient-specific factors. Such considerations include renal function and concurrent medications. Adjustments in dosage may mitigate adverse effects and enhance therapeutic outcomes.
Misoprostol Precautions
Misoprostol carries specific precautions due to its pharmacological action. Patients with a history of allergy to prostaglandins should avoid use. Misoprostol may induce uterine contractions; contraindication exists in pregnancy when not used for induction.
Gastrointestinal disorders warrant careful monitoring. The drug may exacerbate conditions such as inflammatory bowel disease. Adequate hydration and nutritional support are advised during therapy.
Missed Dose
In cases of missed doses, patients should take Misoprostol as soon as remembered. However, if the time nears the next scheduled dose, the missed dose should be skipped. Double dosing should be avoided to prevent potential toxicity.
Establishing a routine can aid adherence. Patients should discuss dosing concerns with healthcare providers. Consistency enhances efficacy and safety of therapy.
Adverse Effects
Misoprostol is associated with several adverse effects. Commonly reported symptoms include diarrhea and abdominal pain. These effects often subside with continued use. However, persistent symptoms require medical attention.
Less frequent adverse reactions include headaches and dizziness. Patients experiencing severe reactions should seek immediate care. Monitoring by healthcare professionals can ensure safe and effective use.
Further information on Misoprostol is available through resources like the NCBI website.
Misoprostol for Sale Online
The online marketplace offers Misoprostol for consumer access. Digital platforms provide a range of products. Verification of sources is critical to ensure authenticity. Regulatory guidelines govern pharmaceutical sales online. Consumers should prioritize reputable sites to avoid counterfeit products.
Consultation with healthcare professionals remains paramount. Clinicians can guide appropriate usage and monitor therapy. Informed choices bolster patient safety and therapeutic success.